Advanced Nutritional Supplement for Diabetics Clinically Proven to Improve Impaired Glucose Tolerance and Hyperinsulinemia

Diabetes is a major health concern in this country with $92 billion dollars being spent annually for health care. According to the National Diabetes Association, 16 million people in the U.S. have diabetes and less than 1/2 aren't' t even aware that they have it.

Diabetes ranks as the number 4 cause death in America with 178,000 associated deaths annually. 18 - 24,000 people lose their eyesight and more than 20,000 diabetics are treated for renal disease. Diabetes is the most frequent cause of non- traumatic loss of limbs each year.

Clinical conditions of diabetes are excessive thirst, frequent urination in large volume, unusual weight loss, blurred vision, high levels of glucose and increased hydrogen ions. The two types of diabetes are TYPE I (IDDM, or insulin dependant), often called juvenile diabetes, and TYPE II (non- insulin dependant) or adult onset diabetes with blood insulin concentration being elevated.

TYPE I makes up 10% of the cases with the majority being TYPE II. TYPE II diabetics are not able to move glucose into the muscle and fat cells which consist of more than 60% of total body cells. Fortunately, research in this area using natural medicines, diet and exercise is growing rapidly. Controlling TYPE II diabetes is now possible with the new formula exclusively available from PHP.

This formula is a patented formula (patent# 5, 411, 748), backed by a double blind study. Pro Z GL was developed by Dr. M.K. Song, a medical research scientist from the UCLA Medical Center. Dr. Song has been engaged in the study of intestinal zinc absorption mechanisms and the clinical implications of altered zinc absorption for more than 20 years, with over 70 published papers to his credit.

Current Knowledge on Zinc and It' s Influence on Clinical Manifestation on Diabetes Zinc

• is involved in almost all disease states and health problems. It activates over 300 metallo- enzymes, including nucleic acid polymerases (cell growth and repair), super oxide dismutase (antioxidant), peptidase (protein digestion), alkaline phosphates, and lactic and alcohol dehydrase. It has been well documented that zinc plays a key role in the regulation of insulin production by the pancreas and glucose utilization by muscle and fat cells.

Zinc deficiency causes reduction or inhibition of the insulin manufacturing process in the pancreas, because cells cannot synthesize protein under zinc deficient conditions and this often causes gene mutation. More importantly, the ability to utilize glucose by the organ cells is impaired in the zinc deficient state. It has been proven that zinc stimulates glucose transporter translocation from inside cells toward the membranes so that glucose uptake by the cells is increased.
It is equally important to know that the zinc metabolic cycle is only 5 hours long and most of the metabolized zinc is excreted back through the small and large intestines. Pro Z GL is a unique, patented formula containing 100 mg of amino acid chelated zinc, bovine prostate powder, chromium and inositol in a base of lecithin and safflower oil.

The known chemical constituents which affect the intestinal zinc absorption mechanisms are: protaglandins, citric acid, picolinic acid, metallothionein metabolites, L- histidine, arachidonic acid and Cyclo- HisPro. Cyclo- HisPro is a major thyrotropin- releasing hormone metabolite and is present in large quantities in the prostate and requires zinc for its synthesis.

These zinc absorption agents are richly packed into the prostate. Animal prostate extract has been recently identified as the most powerful zinc absorption stimulator. It appears as though all of these constituents contained in the prostate may act synergistically to regulate zinc metabolism in the organ cells of diabetics. Further, Glucozin contains 300 mg of prostate substance.